The Amputee Coalition – the leading national organization for people with limb loss – recognizes the value of clinical research in identifying needs, evaluating care, and developing new technologies for people with limb loss.
If you are a researcher and wish to submit an application for Amputee Coalition’s participation in recruitment as described in the policy, please send an e-mail notification to firstname.lastname@example.org.
Learn About Clara and Other National Trials
If you are interested in exploring a national database of clinical trials, try out the Clara Health tool or learn more about the Amputee Coalition’s partnership by scrolling down on mobile or checking the left hand navigation on a laptop.
Projects Approved for Amputee Coalition Participation
The project(s) on this page are those who have completed all the necessary documentation to assure that the research project’s human subject protocols are approved through a recognized institution’s Institutional Review Board and has provided a statement that there are no commercial conflicts of interest. This listing does not imply endorsement of the Amputee Coalition. Research projects are listed as a service to researchers and the limb loss community. The Amputee Coalition is not responsible for the conduct of the researchers. The sponsoring institution assumes responsibility for researcher conduct.
Please click this link : https://tourocollege.az1.qualtrics.com/jfe/form/SV_cYd43YYWRMTed25 to review the informed consent form and participate in the study.
Study volunteers must meet the following criteria:
- Be age 18 or older
- With below the knee amputation
- Willing to come in for multiple visits for as few as 6 months
- Visits Include:
- 1 blood draw
- 1 skin biopsy
- Up to 6 skin injections
- Visits Include:
Compensation for time and travel available up to $500
Funded by Maryland Stem Cell Research Fund; National Institute Of Arthritis & Musculoskeletal & Skin Diseases; Department of Defense (DoD)
If interested, please contact us:
- Age 18 and older
- Upper and/or lower limb loss (at the wrist/ankle or higher)
- At least one-year post amputation
It is believed that there are physical, psychological, and social differences between men and women with amputation, though there is currently little evidence to show this. Your participation will help to build this evidence! Participation in this study is voluntary and there is no cost to participate. All responses are confidential.
Click here: http://www.limblossmatters.com
The survey will take approximately 25 minutes.
You may be eligible if you are:
- use at least one upper extremity prosthetic device (of any kind).
- are willing to wear motion monitors for 72 hours.
- older than 18
No lab visits are required. We provide monetary compensation for your time. For more information, please call 573-882-4572 or email email@example.com.
The principal investigator of this study is Scott H. Frey, Ph.D., Ed.M. The IRB number is 2008784.
Why is this research important?
Performance tests can provide clinicians and researchers with valuable information about an individual prosthesis user’s mobility. Tests available today can take a long time to administer or include tasks that are not appropriate for all types of people. This study is being conducted to develop a new test of mobility that can be administered quickly, provides useful information about each individual, and measures well across a broad range of users. The test we are developing will be free for clinicians and researchers to use when the study is complete.
What will you be asked to do?
Volunteers will be asked to come to the Marriott Rivercenter San Antonio (101 Bowie St, San Antonio, TX 78205) for a single test session. The session will last about 90 minutes. Participation in the study will include first completing a brief survey that asks questions about your health and the activities you do with your prosthesis. You will then be asked to perform a variety of tasks, such as standing still, sitting in and standing up from a chair, walking between cones, stepping over objects, and climbing several steps. Participating in this study is voluntary and there is no cost to participate. You will receive $50 for participating in the study. See more about the study at https://mobility-study.org.
What kinds of people are we looking for?
You are eligible to participate if you are:
– 18 years of age or older
– Able to read, write, and understand English
– Have an amputation in one leg between the ankle and hip
– Use a prosthesis to transfer or walk (and have used the prosthesis for at least 3 months)
– Have no other health conditions (such as another amputation) that affect their balance or ability to walk
How can I learn more or volunteer to participate?
Please contact our UWCORR study coordinators at 1-800-504-0564 (phone) or firstname.lastname@example.org (email) to speak with one of our research staff. They can tell you more about the study, answer any questions you might have, and help you determine if this study is right for you. If you are eligible and interested in participating, you can sign up for the study on July 25th, 26th, or 27th (morning, afternoon, and evening times are available).
This study (UW IRB #3260) is being conducted by investigators at the University of Washington and University of Miami. The study is sponsored by the US National Institutes of Health (Award Number R01HD065340, PI: Brian Hafner, PhD).
Thank you for helping us with this important research.
Brian J. Hafner, PhD
University of Washington Center on Outcomes Research in Rehabilitation (UWCORR)
If you are one of thousands of people in the United States who suffers from chronic pain due to lower extremity amputation you may be eligible to participate in a study. This study uses mild electrical stimulation to provide pain relief in people with post-amputation residual limb (stump) or phantom limb pain.
The device and all study-related care are provided at no cost.
You may be eligible to participate in this study if:
- You are 21 years of age or older
- You have had a lower extremity amputation
- You are experiencing residual limb (stump) and/or phantom limb pain
To learn more about the study and to see if you may qualify, please visit our website at amputeepainstudy.com.
The purpose of the survey is to help medical professionals learn how we can better serve families and their children with limb differences and/or amputations.
If you are a parent of a child who was born with a limb difference and/or a child with an amputation, please follow the link below. The survey will take approximately 10 minutes.
This is a study that has been approved by the Institutional Review Board at the University of North Carolina, Chapel Hill. All responses are anonymous. Please contact Julie Titter if you have questions about the study.
Download PDF Flyer
Researchers at the Providence VA Medical Center, led by Dr. Linda Resnik, are currently recruiting participants with upper limb loss or limb difference for two types of study activities:
1) Interviews and Survey of Women : Most research on upper limb prostheses has been conducted with men. Women’s voices have not been heard! We are looking for women with upper limb loss or limb difference to better understand women’s perspectives on prosthesis use, to develop ways to best capture the concerns and priorities of women, and to provide information that will be useful in designing better prostheses.
- Study participation involves one or more telephone interviews or surveys.
- Each telephone interview or survey will take 45 minutes to an hour.
2) In-Person Study of Prosthesis Users: We are seeking men and women with upper limb loss or limb difference to participate in in-person study activities to understand how different types of prostheses and terminal devices compare to each other. We need your help to make this the largest study comparing upper limb prosthetic devices, controls and suspension methods.
This study will provide evidence to help consumers and clinicians make informed choices about upper limb prosthetic devices. It will also provide comparative data that can be used to evaluate the benefits of new technologies. Our results will be useful to the amputee community, and to third party payers who seek evidence about the benefits of newer and more expensive technologies.
- If you are eligible and interested in being a part of our study, you will travel to one of our 5 study sites to participate in surveys and tests to see how well you are able to do everyday activities with your prosthesis.
- Study participation involves two visits, about one year apart. Study activities on-site take about 3 hours.
- All participants will receive compensation for their time.
- We may pay for your travel if you live more than 2 hours from the testing site.
Study activities are funded by the Department of Defense and by VA Rehabilitation Research and Development. Please contact the study research assistant, Anisha Gill, at 401-273-7100 x6262 to determine your eligibility and for more information, or click here.
Are you a person living with type 2 diabetes?
Are you a person with limb loss?
Have you ever thought about participating in research?
We need your input!
We are studying how social support can influence health for people with type 2 diabetes, through a longitudinal nationwide survey being conducted through the University of California, Davis.
Social support can play a vital role in helping people stay healthy.
But how much does social support matter? What type of social relationships matter the most? When do people go to a doctor? Does it matter if you like your doctor?
These are just some of the questions we want to help answer and your input is important to us. If you are a person living with type 2 diabetes, please consider taking this opportunity to tell us about your experiences.
If you participate, you can be entered in a drawing for a chance to win a $100 Amazon gift card! If you cannot participate in the study, but still want to be included in the drawing, please contact the researchers below.
Interested in learning more?
Reach out to us today! Contact our team at TheDiabetesStudy@gmail.com to set up a time to talk.
- Adults over 18 years of age
- Amputation affecting just one leg
- Either a partial foot or below knee amputation
SHE – CHESC No: S15/268
Principal Investigator: Dr Michael Dillon,
Discipline of Prosthetics and Orthotics, La Trobe University.
Ph: +61 3 9479 5889, email: Michael.Dillon@Latrobe.edu.au
Why is the research important?
Partial foot amputation is often preferred to below knee (transtibial) amputation given the belief that quality of life is better with a less invasive amputation surgery. Recent research indicates that quality of life may be the same in people with partial foot and below-knee amputation. Further research is needed to be confident in the advice we give people facing difficult decisions about lower limb amputation.
Am I eligible?
You are eligible to participate in this study if you:
- are over 18 years of age,
- have a partial foot or below knee (transtibial) amputation affecting one leg
What is involved?
If you choose to participate, you will need to complete an online survey of about 20 minutes. The survey will ask for information about your age, cause of amputation and amputation level as well as things that influence quality of life. The survey does not ask for personally identifying information, like your name, address or specific medical information. All the information you submit is anonymous. There is no way for the researchers to identify you from the data.
Where can I find out more?
You can go online to read the complete Participant Information Statement or complete the survey. Visit: http://www.surveymonkey.com/r/amputation-qol
Time Commitment: 60 minutes
Potential Compensation: $50
Please contact Michayla Petel of the Delaware Limb Loss Studies at (302) 831-7142 if you are interested.
University of Delaware,
Independence Prosthetics – Orthotics, Inc.
Volunteers needed for participation in a prosthetics research study
To be eligible you must:
have a below-the-knee or an above-the-knee amputation
use a prosthesis in & outside the home.
Potential Compensation: $50
Time Commitment: ~3 hours
Contact us at (302) 831-7142 for information.
University of Delaware – Delaware Limb Loss Studies
Daniel J. Lee, PT, DPT, GCS
To all lower extremity amputees…
Are you 18 years of age or older?
Do you use a prosthetic liner?
Are you willing to complete a 5 to 10-minute online survey?
A University of Pittsburgh Master of Science in Orthotics and Prosthetics student is studying the effect that the various climate regions of the United States has on the occurrence and severity of hyperhidrosis (excessive sweating) in lower extremity amputees who use prosthetic liners and the interaction effect of climate region, prosthetic liner type, and physical activity.
Please follow the link below to complete the short survey
Any questions or concerns can be directed to Geoffrey Osik at GJO5@pitt.edu
*there are no foreseeable physical or emotional risks to participation | there will be no reimbursement for participation*
….If so, we would like to know more!
My research is on communication styles between people who have had an amputated limb and their prosthetist. The survey should take around 20-30 minutes to complete, and people who are interested in completing the survey can access it by copying and pasting the link below into their website browser:
if participants wish to get in touch, my email is:
Are pain, ease of prosthetics use, or sensation important to you as a person with limb loss?
You may qualify for research studying how people think about risks and benefits of new limb prosthetic devices. We want to know your preferences about prosthetics. You will participate in a computer survey, at your convenience, about your experience with limb loss. This should take you about 30-45 minutes. You will receive $25 USD for your participation, upon completion.
If you have any questions or to learn more about this survey, please contact us at
Phone: (415) 990-1012
- Improve control of prosthetic limbs
- Restore sensation from amputated limb
- Reduce phantom limb pain
You will be compensated for your time.
University of Pittsburgh
Rehab Neural Engineering Labs
3520 Fifth Avenue
Pittsburgh, PA 15213
For more information
This study involves a telephone interview that will last 30-40 minutes. Women who complete the interview will receive a $20 Amazon Gift Card for participating.
If you are interested in learning more about the study, please contact Suzanne Smeltzer, EdD, RN by e-mail at Suzanne.email@example.com or by phone at 610-519-6828.
Amputees, 18-65 years old, who have a below the knee amputation, who are
currently using a prosthesis. Participants must be at least 1 year post-amputation and able
to walk comfortably with their prosthesis for 30 minutes. Participants must be free of any
serious heart, lung, nervous system disorder, or leg injuries.
What does your participation entail?
Initially, you will be asked to complete a general screening. If you are interested and
eligible for the study, you will be asked to complete the consent process and take part in
20 research visits, taking place at the Providence Veterans Affairs Medical Center. The
purpose of this study is to evaluate the effectiveness of a new type of gait training using
Participants will be compensated for their time and effort.
For more information call:
Jesse McVaney, Research Assistant
(401) 273-7100 x 6208
We would like to hear from you if your use of a prosthetic limb is due to either amputation or congenital limb absence as long as you have spent some time using a prosthesis.
Please follow this link to a University webpage detailing more information on the research and how to participate or enquire further about the study. Recruitment from 1st June 2016 to 31st May 2017 –
Andrew Hodrien (PhD researcher)
Who can participate?
- Individuals who are 18 years or older and have at least one amputation
- Individuals who have OR have never received a massage therapy treatment
What does participation involve?
- Completion of an online survey -‐ between 20 to 30 minutes
Access the survey https://redcap.uits.iu.edu/surveys/?s=HAWRN4JJ87
**In appreciation of participants’ time, each who completes a survey will be entered to win a $20 Amazon gift card!**
If you would like more information or have any questions, please contact Dr. Niki Munk by phone: 317-‐278-‐8658 or email: firstname.lastname@example.org
This study has been approved by Indiana University Institutional Review Board, #1505574988)
- Major Amputation
- 18 years of age or older
- Access to the internet using a computer, tablet or phone
If you are eligible and agree to participate, you will:
- Complete an online assessment about your pain, your function and how you are doing.
- Complete 8 online lessons at the PALS Online w We estimate it will take 25 minutes to complete each lesson.
- Again complete an online assessment about your pain, your function and how you are doing after finishing the lessons.
- Be contacted by study personnel to participate in either a phone call or focus group to give feedback on the program and your experience with PALS Online.
For your participation in the study you will receive;
- $50 after completing all 8 online lessons,
- $25 for answering the assessment questions at the end of the lessons.
- $25 if you participate in the focus group activity
- You will also help us learn more about how to aid others in their recovery.
If you are interested in learning more and determining if you are eligible for the study, please contact Tricia Kirkhart at email@example.com or 410-502-4453 or go to the website palsamputeelifeskills.org and click on Sign Up Now.
Thank you for taking time to learn our project and your commitment to recovery following limb loss. We look forward to the opportunity to work with you on this project.
We are researching the prevalence of common social and psychological challenges faced by lower limb amputees. Completion of the questionnaire will take approximately 30-45 minutes. We will donate $5.00 to the Amputee Coalition for each completed questionnaire.
For more information please contact: Adam Kohn at (856) 287-5023 or Adam.Kohn@bcm.edu
needs, preferences and abilities of persons with upper limb amputations.
If you are invited to participate, you may be asked to come to the Providence VAMC for an interview,
complete a paper survey or complete a telephone survey. Parking is free, and all volunteers will receive
compensation for their time and effort. Please contact Kate Barnabe at (401) 273-7100 x6272 for more
We are currently seeking upper limb amputees to participate in the study. Participants should live within driving distance to New Haven, Connecticut. Residents of New York City and Boston are welcome to apply. Participants must be daily users of their prosthetic device and must have had the device for 6 months or over.
In the first part of the study participants will wear a head-mounted camera in their own homes while completing typical household tasks. In the second part, participants will travel to our laboratory at Yale University, where they will complete similar activities while their movements are recorded by a motion capture system.
Some further details may be found in the following document:
Participants who complete the study will be compensated $320 in addition to travel expenses.
If you are interested in participating, please contact Dr. Adam Spiers for further details and eligibility evaluation.
Phone number: 203-432-4380.
This study is being sponsored by the Telemedicine and Advanced Technology Research Center
(TATRC) US Army Medical Research & Materiel Command (USAMRMC, Ft. Detrick, MD).
- Be 18 years or older
- Have had a lower limb amputation
- Currently use a prosthetic device
If you are interested in participating in this survey, please click on the link provided below. Any questions or concerns about the survey can be directed to Jessica Carrignan at firstname.lastname@example.org.
This research study requires up to 17 visits over 13 weeks to the Spaulding Rehabilitation Network Research Institute in Charlestown, MA.
You may be eligible to participate if you:
- Are over 18
- Had a lower limb amputation
- Have been experiencing chronic pain for at least 3 months
Earn $25 per visit for your participation.
For more information, please contact the Neuromodulation Center
Phone at 617.952.6151
All participants will be entered into a $50 Amazon gift card drawing.
The findings of this study will be presented at Wesleyan College’s Scholarship Day in April.
If you are interested in participating in this study, please contact Rebecca Otwell at email@example.com
*Participants must be at least 18 years of age
We are looking for people age 18-89 years who:
- have a lower-limb amputation involving one or both legs
- use a prosthesis for at least 6 months
- walk with their prosthesis at least 4 hours per day
If you are interested in learning more about the study and being screened for eligibility, please call Jan Pecoraro at 206-764-2962. This study is open to Veterans and non-Veterans.
Lead Researcher: Glenn Klute, PhD 1660 S. Columbian Way, Seattle WA 98108. This study is funded by the U. S. Department of Veterans Affairs.
- Investigators at Nova Southeastern University are studying the benefits of providing amputee specific evidence based-education in a virtual environment and need your help!
- We are looking for upper and/or lower limb amputees age 18 and older to participate
- You will be paid for completing surveys, reviewing amputee specific educational modules, and giving us your feedback.
If interested, please contact Sandra Winkler, PhD, OTR/L at 352-222-9106, 954-262-1216, or firstname.lastname@example.org.
Researchers at Altec, Inc (http://www.delsys.com) are developing new ways of controlling prosthetic limbs. We are looking for volunteers with transradial (forearm) amputation to participate in a research study where sensors will be placed on the forearm of your residual limb to record muscle activity. You will perform simple muscle contractions intended to open and close the hand of your residual limb.A prosthesis is not required. Single or multiple 2-3 hour recording sessionsmay be requested.
Research will be conducted onsite at Altec Inc, 23 Strathmore Rd, Natick, MA 01760
Payment will be provided on an hourly basis at $20/hr. Reimbursement is available for ground transportation.
Male or female
16-65 years old
At least 3 months post trans-radial amputation
Otherwise healthy with no neurological disorders
Must ambulate without assistance
Prosthetic limb not required for this phase of the study
If you meet the study requirements and are interested in participating, please contact Dr. Serge Roy at (508) 545-8235 or email@example.com for more information.
The outcome of this study may someday allow upper limb amputees to control movements of a prosthesis more naturally and intuitively.
ABOUT THE STUDY
- As a participant, you will be asked to perform low-level physical activities such as arm reaching, feeding motion, opening/closing your hand, and wrist movement.
- The research study will be conducted at NC State University in Raleigh, NC.
- Compensation is $25/hour with a minimum of $50/visit.
- Participants residing far from our testing center may be eligible for travel and lodging reimbursement.
YOU MAY BE ELIGIBLE IF YOU ARE
- Between the age of 18 and 70
- At least 1 year post-amputation
- With amputation between the elbow and wrist
- Free from cognitive impairment
- Free from serious illnesses (i.e. stroke, severe heart disease, etc.)
- Without history of serious illness (cardiac arrest, seizure, etc.)
- Fluent in English (for consent form and appropriate communication)
PLEASE CONTACT US!
For more information, please contact the
program director, Dr. He (Helen) Huang:
Neuromuscular Rehabilitation Engineering Lab
Joint Department of Biomedical Engineering
Studies have shown that people who have amputations may have an increased risk of some of these risk factors.
You may benefit from early detection of risk factors of developing cardiovascular disease. However, no benefit can be guaranteed.
- Over the age of 18
- > 3 months since most recent surgery
- No orthopedic injury treated during past year
Orthopedic injury treated during past year (not major limb loss)
Major limb loss resulting from trauma
- 2 visits (baseline & 5 yr follow-up)
- Each visit ~ 90 minutes
Location of Testing:
- WRNMMC Nutrition Research Laboratory
- WRNMMC Amputee Care Service
- WRNMMC ICHP
If interested, please contact:
Eligibility: Age = 18-45 years
Unilateral transtibial or transfemoral amputation, or no injuries
No upper-extremity amputation(s) above the wrist Current (or no) low back pain
Time Commitment: a single 2-hour visit
Location: Biomechanics Laboratory, America Building (19), Room B314
Possible Benefits: Results from this study could improve our understanding of why persons with lower-extremity amputation are susceptible to low back pain.
For more information, contact:
Brad Hendershot, PhD
America Building (19), Room B-311
1) Over the age of 18
2) Below-knee amputation on only one leg
3) Over a year since your amputation
4) Able to use your prosthesis, but you have difficulty doing high-level activities, such as running or jumping
Location of Testing
Walter Reed National Military Medical Center
- Amputee Center
- Prosthetics and Orthotics Service
- Military and Advanced Training Center
First 6 months: 5 clinic visits and 2 prosthetic fittings
Second 6 months: 2 telephone calls to complete questionnaires
Purpose of Study
The purpose of the study is to learn if there are differences between a powered ankle prosthesis and the unpowered prosthesis you currently
wear. We will look at differences in how you walk in both prostheses, if one allows you to use less energy when you walk, and if one allows you to participate in and perform more activities than the other.
There is no guarantee that you will benefit from this study, however other research studies have shown that the use of a powered ankle prosthesis may decrease the stress on your un-amputated leg and may reduce the energy you require to complete daily tasks.
If interested, please contact:
Your participation would involve filling out short on-line surveys from home. The total time to complete all surveys is 15-20 minutes and you will be compensated for your time.
We are looking for participants that meet the following criteria:
- Must be at least 18 years of age
- Must be at least 1 year since amputation
- Must be using current prosthetic for at least 6 months
- Must have, or have access to an active email account
- Must walk without the use of a cane or walker
- Must answer yes to the following: “I can walk continuously for 6 minutes.”
- Must not currently use a vacuum assisted socket suspension system
For further information, please contact the primary investigator, Noah Rosenblatt, PhD, at 312-996-2747.
This study is funded by the American Orthotic and Prosthetics Association
Qualifications for study participation include:
- One amputated lower limb
- Frequent and recurring amputation pain
- Willingness to undergo surgery
- 21 years of age or older
The purpose of this clinical study is to evaluate whether electrical nerve block is a safe and effective treatment for patients with post-amputation pain. You will not be charged for any study related appointments or procedures.