Psilocybin-assisted therapy for phantom limb pain

Web Development Research Studies

Study Location
University of California, San Diego (UCSD) – San Diego, CA

Research Objective
Primary Aim: To test the hypothesis that it is safe and effective to administer psilocybin to individuals who experience phantom limb pain. Secondary aim: To determine behavioral and neural pain responses during noxious stimulation and at rest before and after psilocybin therapy.

Eligibility Criteria

  • Between 18 and 75 years of age.
  • Must have had an amputation of one extremity (upper or lower limb).
  • Experience phantom limb pain (for 1+ months) rated in intensity of at least 3 out of 10.
  • Must be fluent in the English language.
  • Must adhere to the medication/drug use protocols for the duration of the study (more information can be found on our Clinical Trial Webpage).
  • Must tolerate an MRI scan procedure without sedation.
  • Women of childbearing potential must agree to practice effective means of birth control throughout the duration of the study.
  • Must be accompanied by another individual who can provide transportation to and from the study visits.


  • $600 (upon completion of all required study visits)

Enrollment Closes
September 1, 2027

Time Commitment

  • Approximately 45-60 minutes.

Contact Person
Email:| Phone: 619-432-5278

How to Participate
Please visit our Clinical Trial webpage to speak with a researcher and determine your eligibility.