Study Location
Union Memorial Hospital – Baltimore, MD
University of Michigan – Ann Arbor, MI
Research Objectives
Demonstrate the effectiveness of Regenerative Peripheral Nerve Interface (RPNI) surgery in treating symptomatic neuromas of the hand and digits following amputation using a prospective, observation trial. Determine the improvements in hand function, upper extremity function, and ability to return to work or duty as a result of RPNI surgery.
Eligibility Criteria
- 18 years or older
- History of unilateral digit, multiple digit, or partial hand amputation
- Discrete neuroma pain on clinical exam
- Following standard of care (SOC), confirmation through a local block and/or ultrasound imaging will be performed if indicated
- Must be seen by a hand therapist for at least 6-week trial of desensitization therapy
Compensation Details
$75 for 5 follow up visits
Enrollment Closes
Aug 31, 2026
Time Commitment
6 months (+/- 2 weeks)
Contact Person
Leslie Wilson, PhD | email: Wilson-UpperLimbStudy@ucsf.edu | phone: 415-990-1012
How to Participate
See recruitment flyer or contact Ashley Bartee.